Abstract Healthcare professionals face complex ethical dilemmas in clinical settings in cases involving end-of-life care, informed consent, and surrogate decision-making. These nuanced situations often lead to moral distress among care providers. This paper introduces the Bioethics Artificial Intelligence Advisory (BAIA) framework, a novel and innovative approach that leverages artificial intelligence (AI) to support clinical ethical decision-making. The BAIA framework integrates multiple bioethical approaches, including principlism, casuistry, and narrative ethics, with advanced AI capabilities to provide comprehensive decision support. The framework employs a structured methodology that includes data collection, paradigmatic case review, analysis through "mattering maps," and scenario-based decision reasoning. A detailed analysis of two challenging cases, an end-of-life care decision and a complex conjoined twins case, demonstrates BAIA’s potential to harmonize diverse ethical perspectives while reducing the moral burden […]
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