Whitehead Institute and CSAIL researchers created a machine-learning model to predict and generate protein localization, with implications for understanding and remedying disease. Publication Date: February 13, 2025 Press Inquiries Two micrographs. On the left, small, bright green fuzzy dots appear within a larger space. On the right, the bright green coloration is dispersed throughout most of the space Caption: ProtGPS predicts where a protein will localize in a healthy cell (left) and in the instance of a pathogenic mutation (right). Punctate green dots represent localized proteins. Credits: Images: Henry Kilgore and Lena Afeyan/Whitehead Institute Proteins are the workhorses that keep our cells running, and there are many thousands of types of proteins in our cells, each performing a specialized function. Researchers have long known that the structure of a […]
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